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Comparisons of chromosome Y-substituted mouse strains reveal that the male-specific chromosome modulates the effects of androgens on cardiac functions
BACKGROUND: The C57BL/6J.Y(A/J) mouse strain is a chromosome-substituted line where the original male-specific portion of chromosome Y (MSY) from C57BL/6J mice was substituted for that from A/J mice. In hearts from male C57BL/6J.Y(A/J) and C57BL/6J mice, orchidectomy (ORX) affected in a strictly str...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143463/ https://www.ncbi.nlm.nih.gov/pubmed/27980711 http://dx.doi.org/10.1186/s13293-016-0116-4 |