Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C

AIM: To characterize the role of apolipoprotein B100 (apoB100) in hepatitis C viral (HCV) infection. METHODS: In this study, we utilize a gene editing tool, transcription activator-like effector nucleases (TALENs), to generate human hepatoma cells with a stable genetic deletion of APOB to assess of...

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Detalles Bibliográficos
Autores principales: Schaefer, Esperance A K, Meixiong, James, Mark, Christina, Deik, Amy, Motola, Daniel L, Fusco, Dahlene, Yang, Andrew, Brisac, Cynthia, Salloum, Shadi, Lin, Wenyu, Clish, Clary B, Peng, Lee F, Chung, Raymond T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143762/
https://www.ncbi.nlm.nih.gov/pubmed/28018102
http://dx.doi.org/10.3748/wjg.v22.i45.9954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143762/
https://www.ncbi.nlm.nih.gov/pubmed/28018102
http://dx.doi.org/10.3748/wjg.v22.i45.9954

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