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Inhibition of PKR protects against H(2)O(2)-induced injury on neonatal cardiac myocytes by attenuating apoptosis and inflammation

Reactive oxygenation species (ROS) generated from reperfusion results in cardiac injury through apoptosis and inflammation, while PKR has the ability to promote apoptosis and inflammation. The aim of the study was to investigate whether PKR is involved in hydrogen peroxide (H(2)O(2)) induced neonata...

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Detalles Bibliográficos
Autores principales: Wang, Yongyi, Men, Min, Xie, Bo, Shan, Jianggui, Wang, Chengxi, Liu, Jidong, Zheng, Hui, Yang, Wengang, Xue, Song, Guo, Changfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144063/
https://www.ncbi.nlm.nih.gov/pubmed/27929137
http://dx.doi.org/10.1038/srep38753