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Mitochondria-targeted dodecyltriphenylphosphonium (C(12)TPP) combats high-fat-diet-induced obesity in mice
BACKGROUND: A membrane-penetrating cation, dodecyltriphenylphosphonium (C(12)TPP), facilitates the recycling of fatty acids in the artificial lipid membrane and mitochondria. C(12)TPP can dissipate mitochondrial membrane potential and may affect total energy expenditure and body weight in animals an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144127/ https://www.ncbi.nlm.nih.gov/pubmed/27534841 http://dx.doi.org/10.1038/ijo.2016.146 |