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Mitochondria-targeted dodecyltriphenylphosphonium (C(12)TPP) combats high-fat-diet-induced obesity in mice

BACKGROUND: A membrane-penetrating cation, dodecyltriphenylphosphonium (C(12)TPP), facilitates the recycling of fatty acids in the artificial lipid membrane and mitochondria. C(12)TPP can dissipate mitochondrial membrane potential and may affect total energy expenditure and body weight in animals an...

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Detalles Bibliográficos
Autores principales:	Kalinovich, A V, Mattsson, C L, Youssef, M R, Petrovic, N, Ost, M, Skulachev, V P, Shabalina, I G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144127/ https://www.ncbi.nlm.nih.gov/pubmed/27534841 http://dx.doi.org/10.1038/ijo.2016.146

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