TGF-β regulates phosphorylation and stabilization of Sox9 protein in chondrocytes through p38 and Smad dependent mechanisms

Members of the TGF-β superfamily are important regulators of chondrocyte function. Sox9, a key transcriptional regulator of chondrogenesis, is required for TGF-β-mediated regulation of specific cartilage genes. TGF-β can signal through a canonical, Smad-mediated pathway or non-conical pathways, incl...

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Detalles Bibliográficos
Autores principales: Coricor, George, Serra, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144132/
https://www.ncbi.nlm.nih.gov/pubmed/27929080
http://dx.doi.org/10.1038/srep38616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144132/
https://www.ncbi.nlm.nih.gov/pubmed/27929080
http://dx.doi.org/10.1038/srep38616

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