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Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis

In sarcoidosis, the proinflammatory cytokines interferon gamma, tumour necrosis factor and interleukin-6 are released by monocyte-derived macrophages and lymphocytes in the lungs and other affected tissues. Regulatory receptors expressed on monocytes and macrophages act to suppress cytokine producti...

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Detalles Bibliográficos
Autores principales: Fraser, Simon D., Sadofsky, Laura R., Kaye, Paul M., Hart, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144133/
https://www.ncbi.nlm.nih.gov/pubmed/27929051
http://dx.doi.org/10.1038/srep38689