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Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors

Intracellular pathogens represent a serious threat during early life. Importantly, even though the immune system of newborns may be characterized as developmentally immature, with a propensity to develop Th2 immunity, significant CD8+ T-cell responses may still be elicited in the context of optimal...

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Detalles Bibliográficos
Autores principales: Nazerai, Loulieta, Bassi, Maria R., Uddback, Ida E. M., Holst, Peter J., Christensen, Jan P., Thomsen, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144143/
https://www.ncbi.nlm.nih.gov/pubmed/27929135
http://dx.doi.org/10.1038/srep38666