Cargando…
Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors
Intracellular pathogens represent a serious threat during early life. Importantly, even though the immune system of newborns may be characterized as developmentally immature, with a propensity to develop Th2 immunity, significant CD8+ T-cell responses may still be elicited in the context of optimal...
Autores principales: | Nazerai, Loulieta, Bassi, Maria R., Uddback, Ida E. M., Holst, Peter J., Christensen, Jan P., Thomsen, Allan R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144143/ https://www.ncbi.nlm.nih.gov/pubmed/27929135 http://dx.doi.org/10.1038/srep38666 |
Ejemplares similares
-
Local Antigen Encounter Is Essential for Establishing Persistent CD8(+) T-Cell Memory in the CNS
por: Schøller, Amalie S., et al.
Publicado: (2019) -
PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A
por: Uddbäck, Ida E. M., et al.
Publicado: (2016) -
Functionally Competent, PD-1(+) CD8(+) Trm Cells Populate the Brain Following Local Antigen Encounter
por: Schøller, Amalie Skak, et al.
Publicado: (2021) -
Effector CD8 T Cell-Dependent Zika Virus Control in the CNS: A Matter of Time and Numbers
por: Nazerai, Loulieta, et al.
Publicado: (2020) -
A ‘Furry-Tale’ of Zika Virus Infection: What Have We Learned from Animal Models?
por: Nazerai, Loulieta, et al.
Publicado: (2019)