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Caveolin-1 is an aggresome-inducing protein

Caveolin-1 (Cav1) drives the formation of flask-shaped membrane invaginations known as caveolae that participate in signaling, clathrin-independent endocytosis and mechanotransduction. Overexpression or mutations of Cav1 can lead to its mistrafficking, including its accumulation in a perinuclear com...

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Detalles Bibliográficos
Autores principales: Tiwari, Ajit, Copeland, Courtney A., Han, Bing, Hanson, Caroline A., Raghunathan, Krishnan, Kenworthy, Anne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144149/
https://www.ncbi.nlm.nih.gov/pubmed/27929047
http://dx.doi.org/10.1038/srep38681