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Centrifugal gravity-induced BMP4 induces chondrogenic differentiation of adipose-derived stem cells via SOX9 upregulation

BACKGROUND: Cartilage does not have the capability to regenerate itself. Therefore, stem cell transplantation is a promising therapeutic approach for impaired cartilage. For stem cell transplantation, in vitro enrichment is required; however, stem cells not only become senescent but also lose their...

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Detalles Bibliográficos
Autores principales: Jang, Yeonsue, Jung, Hyerin, Nam, Yoojun, Rim, Yeri Alice, Kim, Juryun, Jeong, Sang Hoon, Ju, Ji Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144493/
https://www.ncbi.nlm.nih.gov/pubmed/27931264
http://dx.doi.org/10.1186/s13287-016-0445-6