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Temporary Depletion of Microglia during the Early Postnatal Period Induces Lasting Sex-Dependent and Sex-Independent Effects on Behavior in Rats

Microglia are the primary immune cells of the brain and function in multiple ways to facilitate proper brain development. However, our current understanding of how these cells influence the later expression of normal behaviors is lacking. Using the laboratory rat, we administered liposomal clodronat...

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Detalles Bibliográficos
Autores principales: VanRyzin, Jonathan W., Yu, Stacey J., Perez-Pouchoulen, Miguel, McCarthy, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144556/
https://www.ncbi.nlm.nih.gov/pubmed/27957532
http://dx.doi.org/10.1523/ENEURO.0297-16.2016