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Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs

There is growing recognition that small open reading frames (sORFs) encoding peptides shorter than 100 amino acids are an important class of functional elements in the eukaryotic genome, with several already identified to play critical roles in growth, development, and disease. However, our understa...

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Detalles Bibliográficos
Autores principales: Li, Hongmei, Hu, Chuansheng, Bai, Ling, Li, Hua, Li, Mingfa, Zhao, Xiaodong, Czajkowsky, Daniel M., Shao, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144680/
https://www.ncbi.nlm.nih.gov/pubmed/27559081
http://dx.doi.org/10.1093/dnares/dsw040