The GATOR1 Complex Regulates Metabolic Homeostasis and the Response to Nutrient Stress in Drosophila melanogaster

TORC1 regulates metabolism and growth in response to a large array of upstream inputs. The evolutionarily conserved trimeric GATOR1 complex inhibits TORC1 activity in response to amino acid limitation. In humans, the GATOR1 complex has been implicated in a wide array of pathologies including cancer...

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Detalles Bibliográficos
Autores principales: Wei, Youheng, Reveal, Brad, Cai, Weili, Lilly, Mary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144957/
https://www.ncbi.nlm.nih.gov/pubmed/27672113
http://dx.doi.org/10.1534/g3.116.035337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144957/
https://www.ncbi.nlm.nih.gov/pubmed/27672113
http://dx.doi.org/10.1534/g3.116.035337

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