Cargando…

Prevention of DNA Rereplication Through a Meiotic Recombination Checkpoint Response

In the budding yeast Saccharomyces cerevisiae, unnatural stabilization of the cyclin-dependent kinase inhibitor Sic1 during meiosis can trigger extra rounds of DNA replication. When programmed DNA double-strand breaks (DSBs) are generated but not repaired due to absence of DMC1, a pathway involving...

Descripción completa

Detalles Bibliográficos
Autores principales: Najor, Nicole A., Weatherford, Layne, Brush, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144958/
https://www.ncbi.nlm.nih.gov/pubmed/27678521
http://dx.doi.org/10.1534/g3.116.033910