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X Chromosome Crossover Formation and Genome Stability in Caenorhabditis elegans Are Independently Regulated by xnd-1

The germ line efficiently combats numerous genotoxic insults to ensure the high fidelity propagation of unaltered genomic information across generations. Yet, germ cells in most metazoans also intentionally create double-strand breaks (DSBs) to promote DNA exchange between parental chromosomes, a pr...

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Detalles Bibliográficos
Autores principales: McClendon, T. Brooke, Mainpal, Rana, Amrit, Francis R. G., Krause, Michael W., Ghazi, Arjumand, Yanowitz, Judith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144962/
https://www.ncbi.nlm.nih.gov/pubmed/27678523
http://dx.doi.org/10.1534/g3.116.035725