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Determination of a Screening Metric for High Diversity DNA Libraries

The fields of antibody engineering, enzyme optimization and pathway construction rely increasingly on screening complex variant DNA libraries. These highly diverse libraries allow researchers to sample a maximized sequence space; and therefore, more rapidly identify proteins with significantly impro...

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Detalles Bibliográficos
Autores principales: Guido, Nicholas J., Handerson, Steven, Joseph, Elaine M., Leake, Devin, Kung, Li A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145166/
https://www.ncbi.nlm.nih.gov/pubmed/27930689
http://dx.doi.org/10.1371/journal.pone.0167088