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MRE11 and ATM Expression Levels Predict Rectal Cancer Survival and Their Association with Radiotherapy Response

BACKGROUND: Aberrant expression of DNA repair proteins is associated with poor survival in cancer patients. We investigated the combined expression of MRE11 and ATM as a predictive marker of response to radiotherapy in rectal cancer. METHODS: MRE11 and ATM expression were examined in tumor samples f...

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Detalles Bibliográficos
Autores principales: Ho, Vincent, Chung, Liping, Revoltar, Maxine, Lim, Stephanie H., Tut, Thein-Ga, Abubakar, Askar, Henderson, Chris J., Chua, Wei, Ng, Weng, Lee, Mark, De Souza, Paul, Morgan, Matthew, Lee, C. Soon, Shin, Joo-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145179/
https://www.ncbi.nlm.nih.gov/pubmed/27930716
http://dx.doi.org/10.1371/journal.pone.0167675