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In Vitro and In Vivo Anti-Allergic and Anti-Inflammatory Effects of eBV, a Newly Developed Derivative of Bee Venom, through Modulation of IRF3 Signaling Pathway in a Carrageenan-Induced Edema Model

BACKGROUND: Bee venom (BV), a type of toxin extracted from honeybees (Apis mellifera), has been empirically and widely used to treat inflammatory diseases throughout Asia. Essential BV (eBV) was developed by removing phospholipase A2 (PLA2) and histamine to lower occurrence of allergic reaction. Thi...

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Detalles Bibliográficos
Autores principales: Chung, Hwa-Jin, Lee, Jinho, Shin, Joon-Shik, Kim, Me-riong, Koh, Wonil, Kim, Min-Jeong, Lee, Jae-woong, Kim, Eun Jee, Lee, In-Hee, Kim, Won Kyung, Lee, Yoon Jae, Lee, Sang Kook, Ha, In-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145209/
https://www.ncbi.nlm.nih.gov/pubmed/27930719
http://dx.doi.org/10.1371/journal.pone.0168120