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Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice

CCR2 is a chemokine receptor expressed on the surface of blood leukocytes, particularly «Ly6C(hi)» inflammatory monocytes and microglia. Signaling through this receptor is thought to influence the immune activity of microglia as well as monocytes egress from the bone marrow (BM) and their traffickin...

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Detalles Bibliográficos
Autores principales: Menasria, Rafik, Canivet, Coraline, Piret, Jocelyne, Gosselin, Jean, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145225/
https://www.ncbi.nlm.nih.gov/pubmed/27930721
http://dx.doi.org/10.1371/journal.pone.0168034