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Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice
CCR2 is a chemokine receptor expressed on the surface of blood leukocytes, particularly «Ly6C(hi)» inflammatory monocytes and microglia. Signaling through this receptor is thought to influence the immune activity of microglia as well as monocytes egress from the bone marrow (BM) and their traffickin...
Autores principales: | Menasria, Rafik, Canivet, Coraline, Piret, Jocelyne, Gosselin, Jean, Boivin, Guy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145225/ https://www.ncbi.nlm.nih.gov/pubmed/27930721 http://dx.doi.org/10.1371/journal.pone.0168034 |
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