Cargando…

Dodecylphosphocholine Micelles Induce Amyloid Formation of the PrP(110-136) Peptide via an α-Helical Metastable Conformation

A peptide encompassing the conserved hydrophobic region and the first β-strand of the prion protein (PrP(110–136)) shown to interact with the surface of dodecylphosphocholine micelles adopts an α-helical conformation that is localized below the head-group layer. This surface-bound peptide has a half...

Descripción completa

Detalles Bibliográficos
Autores principales: Sauvé, Simon, Aubin, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145231/
https://www.ncbi.nlm.nih.gov/pubmed/27930722
http://dx.doi.org/10.1371/journal.pone.0168021