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Oncometabolites: Unconventional triggers of oncogenic signalling cascades

Cancer is a complex and heterogeneous disease thought to be caused by multiple genetic lesions. The recent finding that enzymes of the tricarboxylic acid (TCA) cycle are mutated in cancer rekindled the hypothesis that altered metabolism might also have a role in cellular transformation. Attempts to...

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Detalles Bibliográficos
Autores principales: Sciacovelli, Marco, Frezza, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145802/
https://www.ncbi.nlm.nih.gov/pubmed/27117029
http://dx.doi.org/10.1016/j.freeradbiomed.2016.04.025