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Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study

BACKGROUND: Metabotropic glutamate receptor 3 (mGlu3, mGluR3), encoded by GRM3, is a risk gene for schizophrenia and a therapeutic target. It is unclear whether expression of the receptor is altered in the disorder or related to GRM3 risk genotype. Antibodies used to date to assess mGlu3 in schizoph...

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Detalles Bibliográficos
Autores principales: García-Bea, Aintzane, Walker, Mary A., Hyde, Thomas M., Kleinman, Joel E., Harrison, Paul J., Lane, Tracy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publisher B. V 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145804/
https://www.ncbi.nlm.nih.gov/pubmed/27130562
http://dx.doi.org/10.1016/j.schres.2016.04.015