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Functional Annotation of Ion Channel Structures by Molecular Simulation

Ion channels play key roles in cell membranes, and recent advances are yielding an increasing number of structures. However, their functional relevance is often unclear and better tools are required for their functional annotation. In sub-nanometer pores such as ion channels, hydrophobic gating has...

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Detalles Bibliográficos
Autores principales: Trick, Jemma L., Chelvaniththilan, Sivapalan, Klesse, Gianni, Aryal, Prafulla, Wallace, E. Jayne, Tucker, Stephen J., Sansom, Mark S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145807/
https://www.ncbi.nlm.nih.gov/pubmed/27866853
http://dx.doi.org/10.1016/j.str.2016.10.005