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DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation

Hematopoietic stem cells give rise to all blood cells in a differentiation process that involves widespread epigenome remodeling. Here we present genome-wide reference maps of the associated DNA methylation dynamics. We used a meta-epigenomic approach that combines DNA methylation profiles across ma...

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Detalles Bibliográficos
Autores principales: Farlik, Matthias, Halbritter, Florian, Müller, Fabian, Choudry, Fizzah A., Ebert, Peter, Klughammer, Johanna, Farrow, Samantha, Santoro, Antonella, Ciaurro, Valerio, Mathur, Anthony, Uppal, Rakesh, Stunnenberg, Hendrik G., Ouwehand, Willem H., Laurenti, Elisa, Lengauer, Thomas, Frontini, Mattia, Bock, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145815/
https://www.ncbi.nlm.nih.gov/pubmed/27867036
http://dx.doi.org/10.1016/j.stem.2016.10.019