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High Transmembrane Voltage Raised by Close Contact Initiates Fusion Pore
Membrane fusion lies at the heart of neuronal communication but the detailed mechanism of a critical step, fusion pore initiation, remains poorly understood. Here, through atomistic molecular dynamics simulations, a transient pore formation induced by a close contact of two apposed bilayers is first...
Autores principales: | Bu, Bing, Tian, Zhiqi, Li, Dechang, Ji, Baohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145871/ https://www.ncbi.nlm.nih.gov/pubmed/28018169 http://dx.doi.org/10.3389/fnmol.2016.00136 |
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