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Ménage-à-Trois: The Ratio of Bicarbonate to CO(2) and the pH Regulate the Capacity of Neutrophils to Form NETs
In this study, we identified and characterized the potential of a high ratio of bicarbonate to CO(2) and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation. Both experimental settings increased the rate of spontaneous NET release and potenti...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145884/ https://www.ncbi.nlm.nih.gov/pubmed/28018350 http://dx.doi.org/10.3389/fimmu.2016.00583 |