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A single amino acid determines preference between phospholipids and reveals length restriction for activation ofthe S1P(4 )receptor
BACKGROUND: Sphingosine-1-phosphate and lysophosphatidic acid (LPA) are ligands for two related families of G protein-coupled receptors, the S1P and LPA receptors, respectively. The lysophospholipid ligands of these receptors are structurally similar, however recognition of these lipids by these rec...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514652/ https://www.ncbi.nlm.nih.gov/pubmed/15298705 http://dx.doi.org/10.1186/1471-2091-5-12 |