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Effect of arginine on oligomerization and stability of N-acetylglutamate synthase

N-acetylglutamate synthase (NAGS; E.C.2.3.1.1) catalyzes the formation of N-acetylglutamate (NAG) from acetyl coenzyme A and glutamate. In microorganisms and plants, NAG is the first intermediate of the L-arginine biosynthesis; in animals, NAG is an allosteric activator of carbamylphosphate syntheta...

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Detalles Bibliográficos
Autores principales: Haskins, N., Mumo, A., Brown, P. H., Tuchman, M., Morizono, H., Caldovic, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146650/
https://www.ncbi.nlm.nih.gov/pubmed/27934952
http://dx.doi.org/10.1038/srep38711