Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome

The subterranean blind mole rat, Spalax, experiences acute hypoxia-reoxygenation cycles in its natural subterranean habitat. At the cellular level, these conditions are known to promote genomic instability, which underlies both cancer and aging. However, Spalax is a long-lived animal and is resistan...

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Detalles Bibliográficos
Autores principales: Malik, Assaf, Domankevich, Vered, Lijuan, Han, Xiaodong, Fang, Korol, Abraham, Avivi, Aaron, Shams, Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146665/
https://www.ncbi.nlm.nih.gov/pubmed/27934892
http://dx.doi.org/10.1038/srep38624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146665/
https://www.ncbi.nlm.nih.gov/pubmed/27934892
http://dx.doi.org/10.1038/srep38624

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