Defective Acetylcholine Receptor Subunit Switch Precedes Atrophy of Slow-Twitch Skeletal Muscle Fibers Lacking ERK1/2 Kinases in Soleus Muscle

To test the role of extracellular-signal regulated kinases 1 and 2 (ERK1/2) in slow-twitch, type 1 skeletal muscle fibers, we studied the soleus muscle in mice genetically deficient for myofiber ERK1/2. Young adult mutant soleus was drastically wasted, with highly atrophied type 1 fibers, denervatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shuo, Seaberg, Bonnie, Paez-Colasante, Ximena, Rimer, Mendell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146667/
https://www.ncbi.nlm.nih.gov/pubmed/27934942
http://dx.doi.org/10.1038/srep38745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146667/
https://www.ncbi.nlm.nih.gov/pubmed/27934942
http://dx.doi.org/10.1038/srep38745

Ejemplares similares