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Genomic prediction of coronary heart disease

AIMS: Genetics plays an important role in coronary heart disease (CHD) but the clinical utility of genomic risk scores (GRSs) relative to clinical risk scores, such as the Framingham Risk Score (FRS), is unclear. Our aim was to construct and externally validate a CHD GRS, in terms of lifetime CHD ri...

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Detalles Bibliográficos
Autores principales: Abraham, Gad, Havulinna, Aki S., Bhalala, Oneil G., Byars, Sean G., De Livera, Alysha M., Yetukuri, Laxman, Tikkanen, Emmi, Perola, Markus, Schunkert, Heribert, Sijbrands, Eric J., Palotie, Aarno, Samani, Nilesh J., Salomaa, Veikko, Ripatti, Samuli, Inouye, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Society of Cardiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146693/
https://www.ncbi.nlm.nih.gov/pubmed/27655226
http://dx.doi.org/10.1093/eurheartj/ehw450