Cargando…
Genomic prediction of coronary heart disease
AIMS: Genetics plays an important role in coronary heart disease (CHD) but the clinical utility of genomic risk scores (GRSs) relative to clinical risk scores, such as the Framingham Risk Score (FRS), is unclear. Our aim was to construct and externally validate a CHD GRS, in terms of lifetime CHD ri...
Autores principales: | Abraham, Gad, Havulinna, Aki S., Bhalala, Oneil G., Byars, Sean G., De Livera, Alysha M., Yetukuri, Laxman, Tikkanen, Emmi, Perola, Markus, Schunkert, Heribert, Sijbrands, Eric J., Palotie, Aarno, Samani, Nilesh J., Salomaa, Veikko, Ripatti, Samuli, Inouye, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Society of Cardiology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146693/ https://www.ncbi.nlm.nih.gov/pubmed/27655226 http://dx.doi.org/10.1093/eurheartj/ehw450 |
Ejemplares similares
-
Fine-Scale Genetic Structure in Finland
por: Kerminen, Sini, et al.
Publicado: (2017) -
Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland
por: Strausz, Satu, et al.
Publicado: (2018) -
ANGPTL8 protein-truncating variant associated with lower serum triglycerides and risk of coronary disease
por: Helkkula, Pyry, et al.
Publicado: (2021) -
A data-driven medication score predicts 10-year mortality among aging adults
por: Häppölä, Paavo, et al.
Publicado: (2020) -
Towards a Molecular Systems Model of Coronary Artery Disease
por: Abraham, Gad, et al.
Publicado: (2014)