A Predictive Model for Toxicity Effects Assessment of Biotransformed Hepatic Drugs Using Iterative Sampling Method

Measuring toxicity is one of the main steps in drug development. Hence, there is a high demand for computational models to predict the toxicity effects of the potential drugs. In this study, we used a dataset, which consists of four toxicity effects:mutagenic, tumorigenic, irritant and reproductive...

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Detalles Bibliográficos
Autores principales: Tharwat, Alaa, Moemen, Yasmine S., Hassanien, Aboul Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146749/
https://www.ncbi.nlm.nih.gov/pubmed/27934950
http://dx.doi.org/10.1038/srep38660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146749/
https://www.ncbi.nlm.nih.gov/pubmed/27934950
http://dx.doi.org/10.1038/srep38660

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