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Ultraviolet A Enhances Cathepsin L Expression and Activity via JNK Pathway in Human Dermal Fibroblasts

BACKGROUND: Cathepsin L (CatL) is a cysteine protease with strong matrix degradation activity that contributes to photoaging. Mannose phosphate-independent sorting pathways mediate ultraviolet A (UVA)-induced alternate trafficking of CatL. Little is known about signaling pathways involved in the reg...

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Detalles Bibliográficos
Autores principales: Xu, Qing-Fang, Zheng, Yue, Chen, Jian, Xu, Xin-Ya, Gong, Zi-Jian, Huang, Yun-Fen, Lu, Chun, Maibach, Howard I, Lai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146795/
https://www.ncbi.nlm.nih.gov/pubmed/27901001
http://dx.doi.org/10.4103/0366-6999.194654