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Extracellular matrix components and culture regimen selectively regulate cartilage formation by self-assembling human mesenchymal stem cells in vitro and in vivo

BACKGROUND: Cartilage formation from self-assembling mesenchymal stem cells (MSCs) in vitro recapitulate important cellular events during mesenchymal condensation that precedes native cartilage development. The goal of this study was to investigate the effects of cartilaginous extracellular matrix (...

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Detalles Bibliográficos
Autores principales: Ng, Johnathan, Wei, Yiyong, Zhou, Bin, Burapachaisri, Aonnicha, Guo, Edward, Vunjak-Novakovic, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146812/
https://www.ncbi.nlm.nih.gov/pubmed/27931263
http://dx.doi.org/10.1186/s13287-016-0447-4