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Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment

Abnormally elevated hippocampal Caspase-6 (Casp6) activity is intimately associated with age-related cognitive impairment in humans and in mice. In humans, these high levels of Casp6 activity are initially localized in the entorhinal cortex, the area of the brain first affected by the formation of n...

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Detalles Bibliográficos
Autores principales: Foveau, Benedicte, Albrecht, Steffen, Bennett, David A., Correa, José A., LeBlanc, Andrea C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146837/
https://www.ncbi.nlm.nih.gov/pubmed/27931265
http://dx.doi.org/10.1186/s40478-016-0400-x