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PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment
BACKGROUND: The robust desmoplasia associated with head and neck squamous cell carcinoma (HNSCC) suggests that the tumor microenvironment may be an important component in the pathophysiology of this cancer. Moreover, the high recurrence rate and poor clinical response to chemotherapy and radiation t...
Autores principales: | Watts, Tammara L., Cui, Ruwen, Szaniszlo, Peter, Resto, Vicente A., Powell, Don W., Pinchuk, Irina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146849/ https://www.ncbi.nlm.nih.gov/pubmed/27931212 http://dx.doi.org/10.1186/s12967-016-1091-6 |
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