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Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

BACKGROUND: Histone deacetylase (HDAC) activities modify chromatin structure and play a role in learning and memory during developmental processes. Studies of adult mice suggest HDACs are involved in neural network remodeling in brain repair, but its function in drug addiction is less understood. We...

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Detalles Bibliográficos
Autores principales: Liu, Philip K., Liu, Christina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146867/
https://www.ncbi.nlm.nih.gov/pubmed/27931227
http://dx.doi.org/10.1186/s12929-016-0294-8