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Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling
BACKGROUND: Histone deacetylase (HDAC) activities modify chromatin structure and play a role in learning and memory during developmental processes. Studies of adult mice suggest HDACs are involved in neural network remodeling in brain repair, but its function in drug addiction is less understood. We...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146867/ https://www.ncbi.nlm.nih.gov/pubmed/27931227 http://dx.doi.org/10.1186/s12929-016-0294-8 |