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Increased adipose tissue expression of TLR8 in obese individuals with or without type-2 diabetes: significance in metabolic inflammation

BACKGROUND: The innate immune Toll-like receptors (TLRs) 2/4 are important players in chronic low-grade inflammation called metabolic inflammation in obesity and type-2 diabetes (T2D). While TLR2/4 expression changes associated with metabolic inflammation are known, the adipose tissue expression of...

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Detalles Bibliográficos
Autores principales: Ahmad, Rasheed, Kochumon, Shihab, Thomas, Reeby, Atizado, Valerie, Sindhu, Sardar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146894/
https://www.ncbi.nlm.nih.gov/pubmed/27980459
http://dx.doi.org/10.1186/s12950-016-0147-y