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High-density Association Mapping and Interaction Analysis of PLA2R1 and HLA Regions with Idiopathic Membranous Nephropathy in Japanese

Although recent studies showed anti-PLA2R antibody plays a crucial role in idiopathic membranous nephropathy (IMN), detailed HLA mapping and interaction between the HLA genes and PLA2R1 have not been investigated in IMN. We genotyped across the PLA2R1 gene and the HLA region, using 183 IMN patients...

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Detalles Bibliográficos
Autores principales: Thiri, Myo, Honda, Kenjiro, Kashiwase, Koichi, Mabuchi, Akihiko, Suzuki, Hodaka, Watanabe, Kimio, Nakayama, Masaaki, Watanabe, Tsuyoshi, Doi, Kent, Tokunaga, Katsushi, Noiri, Eisei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146917/
https://www.ncbi.nlm.nih.gov/pubmed/27934873
http://dx.doi.org/10.1038/srep38189