Foxa1 is essential for development and functional integrity of the subthalamic nucleus

Inactivation of transcription factor Foxa1 in mice results in neonatal mortality of unknown cause. Here, we report that ablation of Foxa1 causes impaired development and loss of the subthalamic nucleus (STN). Functional deficits in the STN have been implicated in the etiology of Huntington’s and Par...

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Detalles Bibliográficos
Autores principales: Gasser, Emanuel, Johannssen, Helge C., Rülicke, Thomas, Zeilhofer, Hanns Ulrich, Stoffel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146925/
https://www.ncbi.nlm.nih.gov/pubmed/27934886
http://dx.doi.org/10.1038/srep38611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146925/
https://www.ncbi.nlm.nih.gov/pubmed/27934886
http://dx.doi.org/10.1038/srep38611

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