High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform

With great advances in the field of in vitro brain modelling, the challenge is now to implement these technologies for development and evaluation of new drug candidates. Here we demonstrate a method for culturing three-dimensional networks of spontaneously active neurons and supporting glial cells i...

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Detalles Bibliográficos
Autores principales: Wevers, Nienke R., van Vught, Remko, Wilschut, Karlijn J., Nicolas, Arnaud, Chiang, Chiwan, Lanz, Henriette L., Trietsch, Sebastiaan J., Joore, Jos, Vulto, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146966/
https://www.ncbi.nlm.nih.gov/pubmed/27934939
http://dx.doi.org/10.1038/srep38856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146966/
https://www.ncbi.nlm.nih.gov/pubmed/27934939
http://dx.doi.org/10.1038/srep38856

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