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Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons
Astrocytes are critical in synapse development, and their dysfunction in crucial developmental stages leads to serious neurodevelopmental diseases, including seizures and epilepsy. Immune challenges not only affect brain development, but also promote seizure generation and epileptogenesis, implying...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147000/ https://www.ncbi.nlm.nih.gov/pubmed/27920126 http://dx.doi.org/10.1083/jcb.201605046 |