Structures of human mitofusin 1 provide insight into mitochondrial tethering

Mitochondria undergo fusion and fission. The merging of outer mitochondrial membranes requires mitofusin (MFN), a dynamin-like GTPase. How exactly MFN mediates membrane fusion is poorly understood. Here, we determined crystal structures of a minimal GTPase domain (MGD) of human MFN1, including the p...

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Detalles Bibliográficos
Autores principales: Qi, Yuanbo, Yan, Liming, Yu, Caiting, Guo, Xiangyang, Zhou, Xin, Hu, Xiaoyu, Huang, Xiaofang, Rao, Zihe, Lou, Zhiyong, Hu, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147005/
https://www.ncbi.nlm.nih.gov/pubmed/27920125
http://dx.doi.org/10.1083/jcb.201609019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147005/
https://www.ncbi.nlm.nih.gov/pubmed/27920125
http://dx.doi.org/10.1083/jcb.201609019

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