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Relative bioavailability of three formulations of galunisertib administered as monotherapy in patients with advanced or metastatic cancer

OBJECTIVE: Galunisertib (LY2157299 monohydrate), an inhibitor of the transforming growth factor β (TGFβ) pathway, is currently under investigation in several clinical trials involving multiple tumor types. The primary objective of this study was to assess relative bioavailability of two new galunise...

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Detalles Bibliográficos
Autores principales: Gueorguieva, Ivelina, Cleverly, Ann, Desaiah, Durisala, Azaro, Analia, Seoane, Joan, Braña, Irene, Sicart, Elisabet, Miles, Colin, Lahn, Michael M, Mitchell, Malcolm I, Rodon, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Just Medical Media Limited 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147053/
https://www.ncbi.nlm.nih.gov/pubmed/27990167
http://dx.doi.org/10.7573/dic.212303