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Disruption of the Glutamate–Glutamine Cycle Involving Astrocytes in an Animal Model of Depression for Males and Females

Background: Women are twice as likely as men to develop major depression. The brain mechanisms underlying this sex disparity are not clear. Disruption of the glutamate–glutamine cycle has been implicated in psychiatric disturbances. This study identifies sex-based impairments in the glutamate–glutam...

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Detalles Bibliográficos
Autores principales: Rappeneau, Virginie, Blaker, Amanda, Petro, Jeff R., Yamamoto, Bryan K., Shimamoto, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147055/
https://www.ncbi.nlm.nih.gov/pubmed/28018190
http://dx.doi.org/10.3389/fnbeh.2016.00231