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Progesterone Alters Kynurenine Pathway Activation in IFN-γ-Activated Macrophages – Relevance for Neuroinflammatory Diseases

We have previously demonstrated that the kynurenine pathway (KP), the major biochemical pathway for tryptophan metabolism, is dysregulated in many inflammatory disorders that are often associated with sexual dimorphisms. We aimed to identify a potential functional interaction between the KP and gona...

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Detalles Bibliográficos
Autores principales: de Bie, J., Lim, C. K., Guillemin, G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147515/
https://www.ncbi.nlm.nih.gov/pubmed/27980422
http://dx.doi.org/10.4137/IJTR.S40332